Primary prevention of age related macular degeneration Current evidence does not support a protective role for dietary antioxidant vitamins

Primary prevention of age related macular degeneration Current evidence does not support a protective role for dietary antioxidant vitamins

Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis.

OBJECTIVE To evaluate the effectiveness of dietary antioxidants in the primary prevention of age related macular degeneration (AMD). DESIGN Systematic review and meta-analysis. DATA SOURCES Search of seven databases without limits on year or language of publication, and retrieval of references in pertinent reviews and articles. METHODS Two reviewers independently searched the databases an...

Evidence-based nutritional advice for patients affected by age-related macular degeneration.

This paper presents the evidence available in the literature on the role of nutrients in preventing the occurrence of age-related macular degeneration (AMD) and its progression to more advanced stages. In our analysis we considered publications on vitamins B, C, E and D, carotenoids (i.e. lutein, zeaxanthin and β-carotene), Ω-3 polyunsaturated fatty acids and zinc published between 2003 and 201...

The Association between Dietary Intake of Antioxidants and Ocular Disease

To assess the association between dietary antioxidant intake and the incidence of the three major oxidative stress-related eye diseases, cataracts, glaucoma, and age-related macular degeneration, 78 cases from the University of Auckland Optometry and Vision Science clinic and 149 controls were recruited. Participants completed an antioxidant food-frequency questionnaire, analysed through multip...

Age-Related Macular Degeneration – Potential Roles for Nutraceuticals in its Prevention and Control

Many lines of evidence point to oxidative stress as a key pathogenic factor in age-related macular degeneration (AMD); the modestly positive results of the AREDS1 study – which evaluated supplemental zinc, vitamin E, vitamin C, and beta carotene in AMD patients provide confirmation for this view, while also pointing to a potential role for nutraceuticals in prevention and management of this syn...